Lexical Compendium

Wait... what is this? Sometimes I come across a word, phrase, idiom, quote, reference, bit of slang, person of interest, etc that either I don't know or I find amusing, interesting, etc. This is a collection of those items so that I can refer back to them in emails, texts, etc.

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"Mice lie and monkeys exaggerate."

Mice lie and monkeys exaggerate.

-- David B. Weiner, Ph.D. Professor, Department of Pathology and Laboratory Medicine Chair, Gene Therapy and Vaccine Program, CAMB Co-Leader Tumor Virology Program, Abramson Cancer Program University of Pennsylvania, Perelman School of Medicine

Dr. Weiner coined this aphorism while musing on the use of NHP (nonhuman primates) in HIV vaccines studies at a conference in 2008. In essence, animal models aren't necessarily predictive of how drugs will work in humans.

The phrase is often used in research papers and by science journalists. I can't recall where I first heard it, but I thought of it recently when a friend shared a blurb about how rapamycin is purported to have anti-aging benefits in humans. Though there is no evidence for this in humans, there have been studies with the drug on mice that have found that they live ~12% longer.


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Tags: quote, aphorism

Date Added: 03 Oct 2024
Date Modified: 11 Dec 2024